Grundmann R, Meyer H
Intensive Care Med. 1982;8(4):179-86. doi: 10.1007/BF01725735.
Colloid osmotic pressure (COP) was followed postoperatively in 55 randomized patients. After minor operations and short-term infusion therapy only small changes of the COP could be observed and it was concluded that after such operations COP measurement is unnecessary. After major surgical interventions, however, COP measurement gave valuable hints. It was shown that even in the case of moderate blood loss replaced by crystalloids an abnormally low COP did not occur. The same applied also to preoperative hemodilution. It was unnecessary to substitute the withdrawn blood with a colloid solution. In addition, COP measurement helped to avoid expensive albumin administrations, and indicated colloid overload in cases of pulmonary edema.
对55例随机分组患者术后的胶体渗透压（COP）进行了跟踪监测。在小型手术和短期输液治疗后，仅观察到COP有微小变化，得出结论：此类手术后无需测量COP。然而，在重大手术干预后，COP测量提供了有价值的线索。结果表明，即使在晶体液替代中度失血的情况下，也未出现异常低的COP。术前血液稀释情况也是如此。无需用胶体溶液替代所抽取的血液。此外，COP测量有助于避免昂贵的白蛋白给药，并在发生肺水肿时提示胶体超负荷。
