Perry T L, Hansen S, Quinn N, Marsden C D
J Neurochem. 1982 Oct;39(4):1188-91. doi: 10.1111/j.1471-4159.1982.tb11514.x.
Free amino acid concentrations were measured by conventional amino acid analysis, and gamma-aminobutyric acid (GABA) concentrations were determined, by an ion-exchange fluorometric technique, in CSF specimens from 16 patients with torsion dystonias and in CSF from a large number of control subjects. The mean CSF GABA concentration of the dystonia patients (97 +/- 11 nmol/L) did not differ significantly from the means for CSF GABA in two groups of adult control subjects. Mean concentrations of all commonly determined amino compounds were normal in the CSF of torsion dystonia patients, except for ornithine, which was modestly but significantly reduced.
通过传统氨基酸分析测量游离氨基酸浓度，采用离子交换荧光技术测定了16例扭转性肌张力障碍患者脑脊液标本以及大量对照受试者脑脊液中γ-氨基丁酸（GABA）的浓度。扭转性肌张力障碍患者脑脊液中GABA的平均浓度（97±11 nmol/L）与两组成年对照受试者脑脊液中GABA的平均浓度相比，差异无统计学意义。除鸟氨酸略有但显著降低外，扭转性肌张力障碍患者脑脊液中所有常见测定的氨基化合物的平均浓度均正常。
