Csillik B, Knyihár-Csillik E, Szücs A
Neurosci Lett. 1982 Jul 20;31(1):87-90. doi: 10.1016/0304-3940(82)90059-3.
Repeated iontophoretic administration of the microtubule inhibitors vinblastine or vincristine to the segmentally related dermatomes of patients suffering from postherpetic, trigeminal and other neuralgias permanently alleviates chronic, autochthonous pain. The beneficial effect of this therapy is probably due to transganglionic degenerative atrophy of primary central sensory terminals in the Rolando substance by blockade of retrograde axoplasmic transport in sensory nerves.
对患有带状疱疹后神经痛、三叉神经痛及其他神经痛的患者，反复经离子导入法给予微管抑制剂长春碱或长春新碱至节段相关皮节，可永久性缓解慢性自发痛。该疗法的有益效果可能是由于感觉神经中逆行轴浆运输受阻，导致罗兰多区初级中枢感觉终末发生跨神经节变性萎缩。
