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妊娠合并血红蛋白SD病伴胆囊炎和胆石症

Hemoglobin SD disease associated with cholecystitis and cholelithiasis in pregnancy.

作者信息

Spinapolice R X, Colmorgen G H, Spisso K

出版信息

Obstet Gynecol. 1982 Sep;60(3):388-90.

PMID:7121920
Abstract

A black multipara was shown, by hemoglobin electrophoresis, to have hemoglobin SD disease. The patient exhibited a typically mild anemia that probably was secondary to folate and iron deficiencies as well as to hemoglobinopathic hemolysis. The course of her pregnancy was complicated by pyelonephritis and hyposthenuria, both of which have been reported in association with hemoglobin SD disease in pregnancy. The patient also was shown to have acute cholecystitis probably superimposed on a chronic cholelithiasis. This latter complication was probably the result of hemolysis due to hemoglobin SD disease. The patient was treated medically with good results, and, despite poor compliance and heroin addiction, delivered a viable infant at term.

摘要

一位黑人经产妇通过血红蛋白电泳显示患有血红蛋白SD病。该患者表现出典型的轻度贫血,这可能继发于叶酸和铁缺乏以及血红蛋白病性溶血。她的孕期过程因肾盂肾炎和低渗尿而复杂化,这两种情况在妊娠期血红蛋白SD病中均有报道。该患者还被发现可能患有急性胆囊炎,可能是叠加在慢性胆石症之上。后一种并发症可能是血红蛋白SD病导致溶血的结果。该患者接受了药物治疗,效果良好,尽管依从性差且有海洛因成瘾,但足月产下了一名存活婴儿。

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