[Characteristics of the immunological response in children to the administration of a live tissue-culture influenza vaccine].

Various immunological tests were used for comprehensive study of vaccination immunity at the cellular level in children inoculated with different strains of influenza A virus. The characteristics of cell-mediated immunity in children vaccinated with a live tissue culture oral influenza vaccine were first obtained. There was a direct relationship between a rise in virus-neutralizing antibody levels and values of blast-transformation reaction. The live tissue culture influenza vaccine was shown to produce in children a short-time decrease in reactivity of lymphocytes, most significant changes occurring in the T-subpopulation of lymphocytes.