Vanharanta H, Eronen I, Videman T
Am J Phys Med. 1982 Oct;61(5):221-8.
The effect of ultrasound therapy on glycosaminoglycan metabolism in articular cartilages, menisci and capsular tissues of rabbit knee was studied using both autoradiography and biochemical methods. Glycosaminoglycans were examined by determining the uronic acid, glucosamine and galactosamine contents and the specific radioactivity of galactosamine of the purified substances. A total of 31 rabbits were used, 13 of which received ultrasound treatment, power 1 W/cm2, to the right knee 5 minutes a day for five days. The specific radioactivity in separated glycosaminoglycans of the medial collateral ligament of the treated knee was 69% higher than that of the controls and 36% higher than that of the contralateral ligament. The same effect was seen in autoradiography. Glycosaminoglycan concentrations of articular cartilage, menisci and collateral ligament were unaltered. The result may indicate that the main effect of ultrasound therapy is on the capsular tissues of a healthy joint.
采用放射自显影和生化方法，研究了超声治疗对兔膝关节软骨、半月板和关节囊组织中糖胺聚糖代谢的影响。通过测定纯化物质的糖醛酸、氨基葡萄糖和半乳糖胺含量以及半乳糖胺的比放射性来检测糖胺聚糖。总共使用了31只兔子，其中13只接受了超声治疗，功率为1W/cm2，右侧膝关节每天治疗5分钟，共治疗5天。治疗侧膝关节内侧副韧带中分离出的糖胺聚糖的比放射性比对照组高69%，比另一侧韧带高36%。放射自显影也观察到了同样的效果。关节软骨、半月板和侧副韧带中的糖胺聚糖浓度未发生改变。结果可能表明，超声治疗的主要作用部位是健康关节的关节囊组织。
