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家族性精神分裂症。精神分裂症中神经运动和注意力异常的一个预测指标。

Familial schizophrenia. A predictor of neuromotor and attentional abnormalities in schizophrenia.

作者信息

Walker E, Shaye J

出版信息

Arch Gen Psychiatry. 1982 Oct;39(10):1153-6. doi: 10.1001/archpsyc.1982.04290100027005.

DOI:10.1001/archpsyc.1982.04290100027005
PMID:7125845
Abstract

Family history of psychopathology may have a role in schizophrenics' attentional and neuromotor functions. Twelve schizophrenics with a schizophrenic biological parent (SFH), 12 schizophrenics with no history of schizophrenia in first- or second-degree relatives (SNFH), 12 psychiatric controls, and 12 normal controls were given brief neuromotor examinations and the continuous performance test (CPT). Statistical analyses indicated that SFH manifested significantly more neuromotor abnormalities than did normal controls. On the CPT, SFH had significantly more errors than SNFH and psychiatric controls and slower reaction times than psychiatric controls.

摘要

精神病理学家族史可能在精神分裂症患者的注意力和神经运动功能中起作用。对12名有精神分裂症生物学父母的精神分裂症患者(SFH)、12名一级或二级亲属无精神分裂症病史的精神分裂症患者(SNFH)、12名精神科对照者和12名正常对照者进行了简短的神经运动检查和连续性能测试(CPT)。统计分析表明,SFH表现出的神经运动异常明显多于正常对照者。在CPT测试中,SFH的错误明显多于SNFH和精神科对照者,反应时间比精神科对照者慢。

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