20世纪80年代的新生儿眼炎：发病率、病因及治疗
Ophthalmia neonatorum in the 1980s: incidence, aetiology and treatment.
作者信息
Pierce J M, Ward M E, Seal D V
出版信息
Br J Ophthalmol. 1982 Nov;66(11):728-31. doi: 10.1136/bjo.66.11.728.
Abstract
In a survey of 450 consecutive births in Southampton a 12% incidence has been found of ophthalmia neonatorum. Bacterial pathogens were isolated from only one-third of the cases, while nonpathogens were isolated from as many cases as controls. There was an incidence of chlamydial infection of 3.7 per 1000 live births, while Neisseria gonorrhoeae could not be found. Chloramphenicol is recommended for topical antibacterial treatment, but chlamydial infection will not respond; it must be considered in 'resistant' cases, when both the neonate and the parents will need treatment with erythromycin or tetracycline.
摘要
在对南安普敦市450例连续分娩的调查中，发现新生儿眼炎的发病率为12%。仅三分之一的病例分离出了细菌病原体，而分离出非病原体的病例数量与对照组相同。衣原体感染的发病率为每1000例活产中有3.7例，未发现淋病奈瑟菌。推荐使用氯霉素进行局部抗菌治疗，但衣原体感染对此无反应；在“耐药”病例中必须考虑到衣原体感染，此时新生儿及其父母都需要用红霉素或四环素进行治疗。
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