Rees E, Tait I A, Hobson D, Karayiannis P, Lee N
Arch Dis Child. 1981 Mar;56(3):193-8. doi: 10.1136/adc.56.3.193.
A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment. C trachomatis was reisolated significantly more often from babies treated only with topical tetracycline for 4 weeks (75%) than from those treated with both topical tetracycline and oral erythromycin for 2 weeks (32%). Reisolation from the eyes was associated with only minor clinical signs. Radiological signs of an inflammatory lesion in the chest were found in 2 of 8 babies examined because of persistent cough. These signs were not associated with high or rising titres of serum chlamydial antibody.
在衣原体结膜炎分离培养呈阳性的婴儿中，发现咽部感染的发生率很高。23例婴儿在治疗前，有12例（52%）的咽部分离出沙眼衣原体，治疗后，34例中有4例（12%）的眼部再次分离出沙眼衣原体，34例中有14例（41%）的咽部再次分离出沙眼衣原体。仅用局部四环素治疗4周的婴儿沙眼衣原体再次分离率（75%）显著高于同时用局部四环素和口服红霉素治疗2周的婴儿（32%）。眼部再次分离出沙眼衣原体仅伴有轻微的临床症状。8例因持续咳嗽接受检查的婴儿中，有2例发现胸部有炎症病变的放射学征象。这些征象与血清衣原体抗体滴度高或上升无关。
