Christie W W, Noble R C
Biol Neonate. 1982;42(1-2):79-86. doi: 10.1159/000241579.
The rates of fatty acid synthesis from 3H2O and [1-14C]-acetate as substrates have been determined in sheep placental tissue and maternal and fetal adipose tissues in vitro. The tissue was obtained from sheep approximately 28 or 3 days from parturition. Placental tissue synthesised fatty acids at an appreciable rate and newly synthesised fatty acids were apparently transferred from the tissue to the incubation medium. When the results were expressed per unit of tissue weight, fetal adipose tissue synthesised fatty acids much more rapidly than did placental tissue but because there was much more of the latter tissue, the total amounts of fatty acids synthesised by each were comparable. However, it appeared that most of the fatty acids (approximately 80%) in the fetus must have been derived from the maternal plasma. The nature of the fatty acids synthesised de novo was investigated, as was the manner of their esterification.
已在体外测定了绵羊胎盘组织以及母体和胎儿脂肪组织中以3H2O和[1-14C] -乙酸盐为底物的脂肪酸合成速率。组织取自分娩前约28天或3天的绵羊。胎盘组织以可观的速率合成脂肪酸，新合成的脂肪酸显然从组织转移到了孵育培养基中。当结果以单位组织重量表示时，胎儿脂肪组织合成脂肪酸的速度比胎盘组织快得多，但由于胎盘组织量更多，两者合成的脂肪酸总量相当。然而，似乎胎儿体内的大部分脂肪酸（约80%）一定来自母体血浆。对从头合成的脂肪酸的性质及其酯化方式进行了研究。
