Olivereau M, Olivereau J
Cell Tissue Res. 1982;225(3):487-96. doi: 10.1007/BF00214799.
Freshwater eels were adapted to calcium-free sea water (SW) or 1/3 Ca-free SW. Survival was generally poor in Ca-free SW, although three eels were still in good condition after 19-30 days; survival in 1/3 Ca-free SW was excellent. Osmotic disturbances (increase of plasma osmolarity and sodium levels), which initially occur in Ca-free SW, were no longer detectable after 19-30 days, or in eels in 1/3 Ca-free SW after one month. Plasma calcium sharply decreases initially; it is less depressed after 19-30 days and in 1/3 Ca-free SW. Alterations in the mucus production may be involved in the osmotic changes. Under these conditions no clear stimulation of the calcium-sensitive (Ca-s) cells of the pars intermedia was registered, but in Ca-free SW (1/3 or full strength) the inhibitory effect normally observed in SW does not occur. In a hyperosmotic environment, other ion(s), possibly magnesium, may reduce the response of the Ca-s cells to a lack of environmental calcium.
淡水鳗鱼被置于无钙海水（SW）或1/3无钙SW中。在无钙SW中，存活率通常较低，不过有三条鳗鱼在19 - 30天后仍状况良好；在1/3无钙SW中的存活率则很高。最初出现在无钙SW中的渗透紊乱（血浆渗透压和钠水平升高），在19 - 30天后不再能检测到，或者在置于1/3无钙SW中的鳗鱼一个月后也不再能检测到。血浆钙最初会急剧下降；在19 - 30天后以及在1/3无钙SW中，其下降幅度较小。黏液分泌的改变可能与渗透变化有关。在这些条件下，中间部的钙敏感（Ca - s）细胞未出现明显的刺激，但在无钙SW（1/3强度或全强度）中，通常在SW中观察到的抑制作用并未出现。在高渗环境中，其他离子（可能是镁）可能会降低Ca - s细胞对环境中钙缺乏的反应。
