Oertel D, Schein S J, Kung C
J Membr Biol. 1978 Oct 19;43(2-3):169-85. doi: 10.1007/BF01933477.
Voltage clamp studies show that the wild-type membrane of Paramecium tetraurelia contains a conductance component which is sensitive to hyperpolarization. This component manifests itself as "anomalous", or "inward going", rectification of membrane voltage in response to applied constant current pulses and as a "hyperpolarizing spike" when no K is added to the external solution (Y. Satow, C. Kung, 1977. J. Comp. Physiol. 119:99). Like the conductances which underlie anomalous rectification in other cells, the hyperpolarization-sensitive conductance in Paramecium is specific for K, and the magnitude of the voltage-dependent conductance change depends not only on voltage but also on external potassium concentration. The internal potassium ion concentration of Paramecium is calculated to be between 17 and 18mM.
电压钳研究表明，四膜虫的野生型膜含有一种对超极化敏感的电导成分。该成分表现为对施加的恒定电流脉冲的膜电压“异常”或“内向”整流，并且在外部溶液中不添加钾时表现为“超极化尖峰”（Y. 佐藤，C. 孔，1977年。《比较生理学杂志》119:99）。与其他细胞中构成异常整流基础的电导一样，四膜虫中对超极化敏感的电导对钾具有特异性，并且电压依赖性电导变化的幅度不仅取决于电压，还取决于外部钾浓度。四膜虫内部钾离子浓度经计算在17至18毫摩尔之间。
