草履虫热敏感品系突变的遗传分析
Genetic Analyses of Heat-Sensitve Pawn Mutants of PARAMECIUM AURELIA.
机构信息
Department of Biological Sciences, University of California Santa Barbara, California 93106.
出版信息
Genetics. 1973 Sep;75(1):49-59. doi: 10.1093/genetics/75.1.49.
Heat-sensitive Pawn (ts Pawns) of Paramecium aurelia behaved normally when grown at 23 degrees but failed to avoid strong stimuli at 35 degrees . Four of the five ts Pawn lines tested were found to be allelic at a locus known also to carry temperature-independent Pawn mutations. The fifth ts Pawn line complemented all the conditional and unconditional Pawn mutants of the two known loci. This result, together with the patterns of F(2) segregation from various crosses, suggested the existence of a third Pawn locus. An additive effect of the unlinked ts Pawn genes was observed. These findings and the significance of ts Pawns as experimental material in behavioral and physiological research are discussed.
温度敏感型帕氏草履虫棋子（ts Pawns）在 23 度下生长时表现正常，但在 35 度时无法避免强烈刺激。在五个测试的 ts Pawn 品系中，有四个在已知携带温度不依赖型棋子突变的基因座上是等位基因。第五个 ts Pawn 品系补充了两个已知基因座上所有条件和无条件的棋子突变体。这一结果，以及来自各种杂交的 F2 分离模式，表明存在第三个棋子基因座。未连锁的 ts Pawn 基因的加性效应得到了观察。这些发现以及 ts Pawns 作为行为和生理研究实验材料的意义将在文中进行讨论。
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