Briedigkeit H, Schimmelpfennig R, Buder R, Precht K, Dröseler H
Infection. 1982;10(4):219-22. doi: 10.1007/BF01666914.
A total of 60 patients with chronic urinary tract infections were included in this comparative study. 29 patients received cinoxacin and 31 nalidixic acid for a period of ten days. There were five therapy failures in the cinoxacin group and nine in the nalidixic acid group. Drug-related side-effects were reported by 11 patients in the cinoxacin group and by 13 patients in the nalidixic acid group. Gastrointestinal and central nervous disturbances were the adverse reactions which occurred most frequently. In all cases side-effects disappeared quickly after therapy was discontinued.
本对比研究共纳入60例慢性尿路感染患者。29例患者接受西诺沙星治疗，31例患者接受萘啶酸治疗，疗程均为10天。西诺沙星组有5例治疗失败，萘啶酸组有9例治疗失败。西诺沙星组有11例患者报告了与药物相关的副作用，萘啶酸组有13例。胃肠道和中枢神经紊乱是最常出现的不良反应。在所有病例中，停药后副作用很快消失。
