• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

New taxanes from Taxus brevifolia.

作者信息

Kingston D G, Hawkins D R, Ovington L

出版信息

J Nat Prod. 1982 Jul-Aug;45(4):466-70. doi: 10.1021/np50022a019.

DOI:10.1021/np50022a019
PMID:7130988
Abstract

The isolation of two taxanes from Taxus brevifolia Nutt. is described, together with the isolation of two acetylated taxol derivatives from an acetylated fraction from the same plant. The compounds were identified on the basis of their spectroscopic properties as taxa-4(20),11-diene-2 alpha, 5 alpha, 7 beta, 9 alpha, 10 beta, 13 alpha-hexaol 2,7,9,10,13-pentaacetate (1) (decinnamoyltaxinine J), 10-deacetylbaccatin III (2), taxol 2',7-diacetate (3), and 10-deacetyltaxol 2',7-diacetate (4).

摘要

相似文献

1
New taxanes from Taxus brevifolia.
J Nat Prod. 1982 Jul-Aug;45(4):466-70. doi: 10.1021/np50022a019.
2
19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana.
J Nat Prod. 1981 May-Jun;44(3):312-9. doi: 10.1021/np50015a013.
3
Brevitaxin, a new diterpenolignan from the bark of Taxus brevifolia.短叶紫杉素,一种从短叶红豆杉树皮中提取的新型二萜木脂素。
J Nat Prod. 1995 Apr;58(4):583-5. doi: 10.1021/np50118a017.
4
α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana.来自喜马拉雅红豆杉茎皮的具有α-葡萄糖苷酶抑制活性和细胞毒性的紫杉烷二萜类化合物。
J Nat Prod. 2017 Apr 28;80(4):1087-1095. doi: 10.1021/acs.jnatprod.7b00006. Epub 2017 Feb 27.
5
Taxol and related taxanes. I. Taxanes of Taxus brevifolia bark.紫杉醇及相关紫杉烷。I. 短叶红豆杉树皮中的紫杉烷。
Pharm Res. 1993 Apr;10(4):521-4. doi: 10.1023/a:1018937700459.
6
A new large-scale process for taxol and related taxanes from Taxus brevifolia.一种从短叶红豆杉中提取紫杉醇及相关紫杉烷的新大规模工艺。
Pharm Res. 1995 Jul;12(7):1003-10. doi: 10.1023/a:1016206314225.
7
Taxus spp. needles contain amounts of taxol comparable to the bark of Taxus brevifolia: analysis and isolation.红豆杉属植物的针叶中紫杉醇的含量与短叶红豆杉的树皮相当:分析与分离。
J Nat Prod. 1990 Sep-Oct;53(5):1249-55. doi: 10.1021/np50071a017.
8
[Studies on the taxane diterpenes of the heartwood from Taxus mairei].
Yao Xue Xue Bao. 1989;24(9):673-7.
9
In vitro cell cultures obtained from different explants of Corylus avellana produce Taxol and taxanes.从欧洲榛不同外植体获得的体外细胞培养物可产生紫杉醇和紫杉烷。
BMC Biotechnol. 2006 Dec 6;6:45. doi: 10.1186/1472-6750-6-45.
10
[Studies on the chemical constituents of Taxus yunnanensis].
Yao Xue Xue Bao. 1991;26(10):747-54.

引用本文的文献

1
Paclitaxel production from endophytic isolated from sp. of the Northern Himalayan region.从喜马拉雅北部地区的 种分离出的内生菌生产紫杉醇。 (注:原文中“sp.”前缺失具体物种名,翻译存在一定不完整性)
3 Biotech. 2024 Oct;14(10):251. doi: 10.1007/s13205-024-04091-7. Epub 2024 Sep 26.
2
Heterologous expression of taxane genes confers resistance to fall armyworm in Nicotiana benthamiana.紫杉醇基因的异源表达赋予了本氏烟对秋粘虫的抗性。
Plant Cell Rep. 2024 Mar 12;43(4):94. doi: 10.1007/s00299-024-03169-z.
3
Taxanes and taxoids of the genus Taxus - A comprehensive inventory of chemical diversity.
紫杉烷类和紫杉烷类化合物——紫杉属的综合化学成分多样性目录。
Phytochemistry. 2021 Oct;190:112829. doi: 10.1016/j.phytochem.2021.112829. Epub 2021 Jul 27.
4
A Novel Therapeutic Approach for Colorectal Cancer Stem Cells: Blocking the PI3K/Akt Signaling Axis With Caffeic Acid.一种针对结直肠癌干细胞的新型治疗方法:用咖啡酸阻断PI3K/Akt信号轴
Front Cell Dev Biol. 2020 Dec 23;8:585987. doi: 10.3389/fcell.2020.585987. eCollection 2020.
5
Photoacoustic Imaging Quantifies Drug Release from Nanocarriers via Redox Chemistry of Dye-Labeled Cargo.光声成像是通过染料标记货物的氧化还原化学来量化纳米载体的药物释放。
Angew Chem Int Ed Engl. 2020 Mar 16;59(12):4678-4683. doi: 10.1002/anie.201914120. Epub 2020 Jan 24.
6
The Search for Anticancer Agents from Tropical Plants.从热带植物中寻找抗癌剂
Prog Chem Org Nat Prod. 2018;107:1-94. doi: 10.1007/978-3-319-93506-5_1.
7
Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431.紫杉醇产生菌桔黄青霉NRRL 62431的基因组测序与分析
BMC Genomics. 2014 Jan 25;15:69. doi: 10.1186/1471-2164-15-69.
8
(1S,2S,3R,4S,5R,7S,8S,10R,13S)-2-Debenzoyl-10-deacetyl-2-(3-fluoro-benzo-yl)-7,10-bis-(2,2,2-trichloro-eth-oxy-carbon-yl)baccatin III ethyl acetate monosolvate monohydrate.(1S,2S,3R,4S,5R,7S,8S,10R,13S)-2-去苯甲酰基-10-去乙酰基-2-(3-氟苯甲酰基)-7,10-双-(2,2,2-三氯乙氧基羰基)浆果赤霉素III乙酸乙酯单溶剂合物一水合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 2;67(Pt 3):o547. doi: 10.1107/S1600536811002790.
9
Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo.黄芩苷诱导人黏液表皮样癌 Mc3 细胞凋亡的体内外研究。
Invest New Drugs. 2011 Aug;29(4):637-45. doi: 10.1007/s10637-010-9402-x. Epub 2010 Mar 6.
10
A novel method for analyzing mitochondrial movement: inhibition by paclitaxel in a pheochromocytoma cell model.一种分析线粒体运动的新方法:紫杉醇对嗜铬细胞瘤细胞模型的抑制作用。
J Mol Neurosci. 2009 Mar;37(3):254-62. doi: 10.1007/s12031-008-9129-8. Epub 2008 Jul 18.