血浆置换治疗炎性多发性神经病。
The treatment of inflammatory polyneuropathy by plasma exchange.
作者信息
Gross M L, Legg N J, Lockwood M C, Pallis C
出版信息
J Neurol Neurosurg Psychiatry. 1982 Aug;45(8):675-9. doi: 10.1136/jnnp.45.8.675.
Abstract
Observations are reported on six patients with inflammatory polyneuropathy who were treated by plasma exchange. In four cases the polyneuropathy was acute and in two it was chronic or relapsing. Two acute cases and one chronic relapsing case had plasma exchange during a rapidly progressive phase of the disease, and showed a prompt and substantial recovery of function. The other three patients were exchanged when disease activity had reached a plateau. Only minor degrees of improvement were seen in two of these cases. One patient showed an initial mild deterioration before subsequent recovery. There were no significant side effects. These findings are discussed in relation to the pathogenesis and clinical management of inflammatory polyneuropathy.
摘要
报告了6例接受血浆置换治疗的炎性多神经病患者的观察结果。其中4例为急性多神经病，2例为慢性或复发性多神经病。2例急性病例和1例慢性复发性病例在疾病快速进展期接受了血浆置换，功能迅速且显著恢复。另外3例患者在疾病活动达到平台期时进行了置换。其中2例仅见轻微改善。1例患者在随后恢复之前最初有轻度恶化。未出现明显副作用。结合炎性多神经病的发病机制和临床管理对这些发现进行了讨论。
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