Noble R C, Shand J H, Calvert D T
Placenta. 1982 Jul-Sep;3(3):287-95. doi: 10.1016/s0143-4004(82)80005-2.
A study has been made of the comparative distribution and fatty acid compositions of the major lipid fractions of maternal plasma, placenta and fetal plasma of the sheep at approximately 120 days of gestation. Cholesteryl esters and phospholipids constituted the major lipid fractions present in both maternal and fetal plasmas. In the placenta, phospholipids accounted for some 60 per cent of the total lipid present. Within the phospholipids of the maternal and fetal plasmas and placenta, phosphatidylcholine comprised the largest component. Whereas maternal plasma contained high levels of linoleic and arachidonic acids, fetal plasma contained a low proportion only a linoleic acid and high proportions of delta 5,8,11 eicosatrienoic acid and arachidonic acid. In the maternal plasma the arachidonic acid:linoleic acid ratio was only 0.17, but in the fetal plasma the ratio was 3.32. The differences in the lipid and fatty acid compositions between the maternal plasma, fetal plasma and placenta are discussed in relationship to the distinctive polyunsaturated fatty acid metabolism of the fetal and newborn lamb.
对妊娠约120天的绵羊母体血浆、胎盘和胎儿血浆中主要脂质成分的比较分布和脂肪酸组成进行了研究。胆固醇酯和磷脂是母体和胎儿血浆中存在的主要脂质成分。在胎盘中，磷脂约占总脂质的60%。在母体、胎儿血浆和胎盘的磷脂中，磷脂酰胆碱是最大的组成部分。母体血浆中含有高水平的亚油酸和花生四烯酸，而胎儿血浆中仅含有低比例的亚油酸，以及高比例的δ5,8,11二十碳三烯酸和花生四烯酸。母体血浆中花生四烯酸与亚油酸的比例仅为0.17，但胎儿血浆中的该比例为3.32。讨论了母体血浆、胎儿血浆和胎盘之间脂质和脂肪酸组成的差异与胎儿和新生羔羊独特的多不饱和脂肪酸代谢的关系。
