Blenk H, Junge W
Klin Wochenschr. 1978 Oct 1;56(19):973-6. doi: 10.1007/BF01480152.
The distribution of haptoglobin phenotypes (Hp) 1--1, 2--1 and 2--2 in 174 patients suffering from liver cirrhosis was determined and compared with a reference group consisting of 194 healthy subjects. The study revealed a high frequency of the Hp 1--1 phenotype (32%) in the patients as compared with the control group (14%). This difference is statistically highly significant (p less than 0.00025). It was calculated that in individuals of type Hp 1--1, the risk of liver cirrhosis is 4.3-fold higher than in persons with the phenotype Hp 2--2.
测定了174例肝硬化患者中触珠蛋白表型（Hp）1--1、2--1和2--2的分布情况，并与由194名健康受试者组成的参照组进行了比较。研究显示，与对照组（14%）相比，患者中Hp 1--1表型的频率较高（32%）。这种差异在统计学上具有高度显著性（p小于0.00025）。经计算，Hp 1--1型个体患肝硬化的风险比Hp 2--2型个体高4.3倍。
