Zacharias W, Follmann H
Z Naturforsch C Biosci. 1982 Jul-Aug;37(7-8):727-30. doi: 10.1515/znc-1982-7-827.
Marked anomalies, previously unresolved, exist in the CD spectra of oligoadenylates and oligouridylates at the pentamer or tetramer stage, indicating that these molecules differ in conformation from the preceding and the following member of the series. The CD of oligoadenylates retains a positive Cotton effect even at 80 degrees C. Caution must be exerted when predicting oligonucleotide structures from CD spectra.
在五聚体或四聚体阶段，寡腺苷酸和寡尿苷酸的圆二色光谱存在明显的、先前未解决的异常现象，这表明这些分子在构象上与该系列中之前和之后的成员不同。即使在80摄氏度时，寡腺苷酸的圆二色光谱仍保留正科顿效应。从圆二色光谱预测寡核苷酸结构时必须谨慎。
