戊巴比妥对内毒素血症猫节后交感神经放电的抑制作用
Suppression of postganglionic sympathetic discharges by pentobarbital in endotoxic cats.
作者信息
Halinen M O, Hakumäki M O, Sarajas H S
出版信息
Acta Physiol Scand. 1982 Feb;114(2):267-70. doi: 10.1111/j.1748-1716.1982.tb06981.x.
Abstract
Pentobarbital (7-9 mg/kg) profoundly suppressed the sympathetic postganglionic cardiac and splenic discharges in endotoxic cats under chloralose anesthesia. Concurrently, the pre-existent tachycardia was replaced by bradycardia, and the blood pressure fell further. The findings are interpreted to imply a pentobarbital-induced sympatholysis.
摘要
在氯醛糖麻醉下，戊巴比妥（7 - 9毫克/千克）可显著抑制内毒素血症猫的交感神经节后心脏和脾脏放电。同时，先前存在的心动过速被心动过缓所取代，血压进一步下降。这些发现被解释为意味着戊巴比妥诱导的交感神经阻滞。
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