[Comparative study of the dynamics of carbohydrate metabolism in the growth of Candida tropicalis yeasts on n-octadecane and glucose].

The dynamics of carbon metabolism was studied in Candida tropicalis growing on 14C-labeled n-octadecane and glucose by means of the technique of radioactive indicators. The kinetics of incorporation of 14C into the main groups of organic substances in the cell (proteins, nucleic acids+polysaccharides, lipids, free amino acids, organic acids, free carbohydrates+nucleotides) revealed differences in the rate of their synthesis and accumulation. The general features and the major differences in the pathways of carbon metabolism depended on the nature of a carbon substrate. If the yeast used n-octadecane as a source of carbon, the rate of synthesis of the lipid fraction was higher, and the ratio between its components changed as well as the rates of their synthesis.