Chernow B, Finton C, Rainey T G, O'Brian J T
Diabetes Care. 1982 Jan-Feb;5(1):47-9. doi: 10.2337/diacare.5.1.47.
A 19-yr-old woman developed ketoacidosis 7 wk after the delivery of her first child. Despite breast feeding, she had been on a weight reduction diet resulting in a loss of 12 kg/body wt. With the development of a urinary tract infection, the patient became dehydrated and was found to be in ketoacidosis (arterial pH was 7.25 and PaCO2 was 17 mm Hg). The patient did not use alcohol and was nondiabetic. Therapy with adequate calories, intravenous fluids, and an appropriate antimicrobial agent resulted in prompt normalization of the laboratory abnormalities and resolution of the patient's symptoms. The hypothesis is advanced that the postpartum status of the patient put her at particular risk for development of ketoacidosis and that this may represent the first reported episode of "bovine ketosis" in a human.
一名19岁女性在分娩第一胎7周后发生酮症酸中毒。尽管她在母乳喂养，但一直在进行减肥饮食，体重减轻了12千克。随着尿路感染的发展，患者出现脱水，被发现处于酮症酸中毒状态（动脉pH值为7.25，动脉血二氧化碳分压为17毫米汞柱）。该患者不饮酒且无糖尿病史。给予足够热量、静脉补液及适当抗菌药物治疗后，实验室异常迅速恢复正常，患者症状也得以缓解。提出的假设是，患者的产后状态使其特别容易发生酮症酸中毒，这可能是人类中首次报道的“牛酮血症”病例。
