Kireeva I V, Khomchenovskiĭ E I, Pykhtina A A
Farmakol Toksikol. 1982 Sep-Oct;45(5):90-3.
It has been found that paphencyl, preparations II-72 and II-119 decrease to an equal measure the leukocyte count in the peripheral blood and the myelokaryocyte count in animals immunized with sheep red blood cells and in intact CBA mice. The maximal action develops by the 2nd-3rd day after cytostatic administration. Immune reactions of mice were shown to be more susceptible to the action of the drugs under study as compared to hemopoiesis.
已发现，帕芬西尔、制剂II - 72和II - 119能同等程度地降低用绵羊红细胞免疫的动物以及未免疫的CBA小鼠外周血中的白细胞计数和骨髓有核细胞计数。在给予细胞抑制剂后的第2 - 3天出现最大作用。与造血功能相比，小鼠的免疫反应对所研究药物的作用更敏感。
