Chandra D, Thulasimany M, Biswas A R
Indian J Physiol Pharmacol. 1982 Apr-Jun;26(2):147-51.
The uterotropic effect of clofibrate and phenylbutazone was studied in immature female rats. A significant increase in the uterine wet weight was observed following clofibrate and phenylbutazone administration. Clofibrate but not phenylbutazone synergized with the uterotropic effect of ethinyl-oestradiol. Phenylbutazone pretreatment significantly decreased the pentobarbitone sleeping time. The uterotropic effect of clofibrate and phenylbutazone might involve displacement of 17-beta oestradiol (or ethinyl oestradiol) from plasma albumin binding sites in rats.
在未成熟雌性大鼠中研究了氯贝丁酯和保泰松的促子宫生长作用。给予氯贝丁酯和保泰松后，观察到子宫湿重显著增加。氯贝丁酯而非保泰松与炔雌醇的促子宫生长作用协同。保泰松预处理显著缩短了戊巴比妥睡眠时间。氯贝丁酯和保泰松的促子宫生长作用可能涉及大鼠血浆白蛋白结合位点上17-β雌二醇（或炔雌醇）的置换。
