Gary-Bobo C M, Cybulska B
J Antibiot (Tokyo). 1982 Aug;35(8):1068-71. doi: 10.7164/antibiotics.35.1068.
The efficiency in inducing cation permeability of vacidin A, candicidin D and amphotericin B has been compared on small and large lipidic vesicles. Amphotericin B is two times less effective on large than on small vesicles. On the contrary, vacidin A and candicidin D are about ten times more effective on large than on small vesicles. These data are consonant with what is observed on living cells.
已在小型和大型脂质囊泡上比较了杀假丝菌素A、制假丝菌素D和两性霉素B诱导阳离子通透性的效率。两性霉素B对大型囊泡的效果比对小型囊泡的效果低两倍。相反，杀假丝菌素A和制假丝菌素D对大型囊泡的效果比对小型囊泡的效果高约十倍。这些数据与在活细胞上观察到的情况一致。
