在全科医疗中监测抗生素的不良反应。
Monitoring adverse reactions to antibiotics in general practice.
作者信息
Martys C R
出版信息
J Epidemiol Community Health. 1982 Sep;36(3):224-7. doi: 10.1136/jech.36.3.224.
Abstract
In a general practice in Derbyshire 298 patients who had been given antibiotics were questioned about possible adverse reactions to the drug prescribed. Four methods of assessing adverse effects of drugs in the community were used, and a comparison was made of the replies elicited from patients by doctor and health visitor respectively. Significant differences were shown to occur in the way in which each investigator completed the questionnaires. If ancillary staff are to be employed in monitoring adverse effects of drugs in the community on a large scale then they will have to use a method less reliant on the differentiation of incidental symptoms from drug side effects than is required in the present survey.
摘要
在德比郡的一次普通医疗实践中，298名服用过抗生素的患者被询问了对所开药物可能的不良反应。采用了四种评估社区中药物不良反应的方法，并对医生和健康访视员分别从患者那里得到的回答进行了比较。结果显示，每位调查者填写问卷的方式存在显著差异。如果要大规模雇佣辅助人员来监测社区中药物的不良反应，那么他们将不得不采用一种比本次调查所需方法更少依赖于区分偶然症状和药物副作用的方法。
相似文献
1
Monitoring adverse reactions to antibiotics in general practice.在全科医疗中监测抗生素的不良反应。
J Epidemiol Community Health. 1982 Sep;36(3):224-7. doi: 10.1136/jech.36.3.224.
2
Adverse drug reactions due to oral antibiotics prescribed in the community setting - England.社区环境下口服抗生素导致的药物不良反应-英格兰。
Infect Dis (Lond). 2019 Nov-Dec;51(11-12):866-869. doi: 10.1080/23744235.2019.1663918. Epub 2019 Sep 12.
3
[Drug allergy in a population of surgical patients].[外科手术患者群体中的药物过敏]
Rev Esp Anestesiol Reanim. 1998 Dec;45(10):425-30.
4
[Undesirable and adverse effects of drugs in Poland. Antibiotics (other than penicillin) and sulfonamides].[波兰药物的不良及有害效应。抗生素（除青霉素外）及磺胺类药物]
Przegl Dermatol. 1981 May-Jun;68(3):287-93.
5
Prevalence of self-reported drug hypersensitivity reactions among Lithuanian children and adults.立陶宛儿童和成人中自我报告的药物过敏反应患病率。
Allergol Immunopathol (Madr). 2019 Jan-Feb;47(1):32-37. doi: 10.1016/j.aller.2018.05.006. Epub 2018 Sep 20.
6
Allergic reactions to oral drugs: A case/non-case study from an Italian spontaneous reporting database (GIF).口服药物过敏反应：来自意大利自发报告数据库（GIF）的病例/非病例研究
Pharmacol Res. 2008 Sep-Oct;58(3-4):202-7. doi: 10.1016/j.phrs.2008.07.003. Epub 2008 Jul 23.
7
Hypersensitivity reactions during anesthesia. Results from the ninth French survey (2005-2007).麻醉期间的过敏反应。第九次法国调查（2005-2007 年）的结果。
Minerva Anestesiol. 2012 Aug;78(8):868-78. Epub 2012 Mar 22.
8
Allergy to antibiotics in children: an overestimated problem.儿童对抗生素过敏：被高估的问题。
Int J Antimicrob Agents. 2016 Oct;48(4):361-6. doi: 10.1016/j.ijantimicag.2016.08.001. Epub 2016 Aug 12.
9
Frequency of adverse drug reactions in patients with systemic lupus erythematosus.系统性红斑狼疮患者药物不良反应的发生率
J Rheumatol. 2003 Mar;30(3):480-4.
10
A comprehensive 4-year survey of adverse drug reactions using a network-based hospital system.一项使用基于网络的医院系统进行的全面的 4 年药物不良反应调查。
J Clin Pharm Ther. 2012 Dec;37(6):647-51. doi: 10.1111/j.1365-2710.2012.01359.x. Epub 2012 May 30.
引用本文的文献
1
Effect of systemic antibiotic and probiotic therapies as adjuvant treatments of subgingival instrumentation for periodontitis: a randomized controlled clinical study.系统抗生素和益生菌治疗作为牙周炎龈下器械治疗的辅助治疗的效果：一项随机对照临床试验。
J Appl Oral Sci. 2022 Mar 23;30:e20210583. doi: 10.1590/1678-7757-2021-0583. eCollection 2022.
2
Eliciting adverse effects data from participants in clinical trials.从临床试验参与者中获取不良反应数据。
Cochrane Database Syst Rev. 2018 Jan 16;1(1):MR000039. doi: 10.1002/14651858.MR000039.pub2.
本文引用的文献
1
STUDIES ON THE EPIDEMIOLOGY OF ADVERSE DRUG REACTIONS. I. METHODS OF SURVEILLANCE.药物不良反应流行病学研究。I. 监测方法。
JAMA. 1964 Jun 15;188:976-83. doi: 10.1001/jama.1964.03060370032007.
2
Intensive hospital monitoring of adverse reactions to drugs.医院对药物不良反应进行强化监测。
Br Med J. 1969 Mar 1;1(5643):531-6. doi: 10.1136/bmj.1.5643.531.
3
Adverse nondrug reactions.药物不良反应。
N Engl J Med. 1968 Sep 26;279(13):678-9. doi: 10.1056/NEJM196809262791304.
4
Adverse drug reactions: the need for detection and control.药物不良反应：检测与控制的必要性。
Am J Epidemiol. 1971 Nov;94(5):405-8. doi: 10.1093/oxfordjournals.aje.a121336.
5
The use of historical data and adverse reaction reporting systems for epidemiologic study.利用历史数据和不良反应报告系统进行流行病学研究。
Am J Epidemiol. 1971 Sep;94(3):210-4. doi: 10.1093/oxfordjournals.aje.a121314.
6
Evaluation of spontaneous reports of adverse reactions to drugs.药物不良反应自发报告的评估
Br Med J. 1972 Sep 23;3(5829):746-9. doi: 10.1136/bmj.3.5829.746.
7
Pattern of drug-induced disease in the community. An unsolved enigma.社区中药物性疾病的模式。一个未解之谜。
Br Med Bull. 1970 Sep;26(3):240-4. doi: 10.1093/oxfordjournals.bmb.a070791.
8
Measurement of side effects of drugs.药物副作用的测量
Br Med J. 1974 Jun 29;2(5921):698-9. doi: 10.1136/bmj.2.5921.698.
9
Side effects of hypotensive agents evaluated by a self-administered questionnaire.通过自行填写问卷评估降压药的副作用。
Br Med J. 1973 Sep 1;3(5878):485-90. doi: 10.1136/bmj.3.5878.485.
10
Drug surveillance utilizing epidemiologic methods. A report from the Boston Collaborative Drug Surveillance Program.利用流行病学方法进行药物监测。波士顿合作药物监测项目的一份报告。
Am J Hosp Pharm. 1973 Jul;30(7):584-92.
Zotero 插件