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p-Xylene metabolism by rabbit lung and liver and its relationship to the selective destruction of pulmonary cytochrome P-450.

作者信息

Smith B R, Plummer J L, Wolf C R, Philpot R M, Bend J R

出版信息

J Pharmacol Exp Ther. 1982 Dec;223(3):736-42.

PMID:7143236
Abstract
摘要

相似文献

1
p-Xylene metabolism by rabbit lung and liver and its relationship to the selective destruction of pulmonary cytochrome P-450.
J Pharmacol Exp Ther. 1982 Dec;223(3):736-42.
2
Effect of p-xylene metabolites, p-methylbenzyl alcohol and 2,5-dimethylphenol, on rat hepatic and pulmonary microsomal metabolism.
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The biotransformation of p-xylene to a toxic aldehyde.
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Specificity of rabbit pulmonary cytochrome P-450 isozymes in the activation of several aromatic amines and aflatoxin B1.兔肺细胞色素P-450同工酶在几种芳香胺和黄曲霉毒素B1激活中的特异性。
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The destruction of pulmonary and hepatic cytochrome P-450 by phthaladehyde.邻苯二甲醛对肺和肝细胞色素P-450的破坏作用。
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Heme enhances hexobarbital metabolism in perfused rat liver after drug-mediated destruction of cytochrome P-450.在药物介导的细胞色素P - 450破坏后，血红素可增强灌注大鼠肝脏中己巴比妥的代谢。
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Enzyme induction by o-xylene inhalation.吸入邻二甲苯引起的酶诱导作用。
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Mechanism-based inactivation of mouse hepatic cytochrome P4502B enzymes by amine metabolites of musk xylene.麝香二甲苯胺代谢产物对小鼠肝脏细胞色素P4502B酶的基于机制的失活作用
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Effect of carbon monoxide on the cytochrome P-450-mediated metabolism of aniline and p-nitroanisole in the isolated perfused rabbit lung.一氧化碳对离体灌注兔肺中细胞色素P - 450介导的苯胺和对硝基苯甲醚代谢的影响。
J Toxicol Environ Health. 1989;27(3):331-40. doi: 10.1080/15287398909531304.

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Whole-body inhalation exposure to 2-ethyltoluene for two weeks produced nasal lesions in rats and mice.大鼠和小鼠经两周全身吸入 2-乙基甲苯后，鼻腔出现损伤。
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A review of environmental and occupational exposure to xylene and its health concerns.对二甲苯的环境与职业暴露及其健康问题的综述。
EXCLI J. 2015 Nov 23;14:1167-86. doi: 10.17179/excli2015-623. eCollection 2015.
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Biochemical effects of Pembina Cardium crude oil exposure in cattle.彭比纳心形原油暴露对牛的生化影响。
Arch Environ Contam Toxicol. 1996 Mar;30(3):349-55. doi: 10.1007/BF00212293.
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m-Xylene inhalation destroys cytochrome P-450 in rat lung at low exposure.低剂量吸入间二甲苯会破坏大鼠肺部的细胞色素P-450。
Arch Toxicol. 1987;61(1):21-6. doi: 10.1007/BF00324543.
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Pulmonary toxicity of inhaled styrene in acetone-, phenobarbital- and 3-methylcholanthrene-treated rats.丙酮、苯巴比妥和3-甲基胆蒽处理的大鼠吸入苯乙烯后的肺毒性
Arch Toxicol. 1990;64(5):365-9. doi: 10.1007/BF01973457.
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Protection against chemical-induced lung injury by inhibition of pulmonary cytochrome P-450.通过抑制肺细胞色素P-450来预防化学诱导的肺损伤。
Environ Health Perspect. 1990 Apr;85:95-100. doi: 10.1289/ehp.85-1568337.