部分回肠旁路术治疗家族性高胆固醇血症。
Partial ileal bypass in treatment of familial hypercholesterolaemia.
作者信息
Chalstrey L J, Winder A F, Galton D J
出版信息
J R Soc Med. 1982 Nov;75(11):851-6. doi: 10.1177/014107688207501105.
The effects of partial ileal bypass have been studied in 7 patients with heterozygous familial hypercholesterolaemia. By the seventh to ninth postoperative day there was a significant fall in plasma cholesterol of 42.8% compared with levels at initial presentation. Thereafter, plasma levels of cholesterol rose by varying degrees, but had stabilized by 3 months with average values 29.5% lower than pretreatment. Debilitating diarrhoea or severe weight loss were not troublesome features of the operation in most patients.
对7例杂合子家族性高胆固醇血症患者进行了部分回肠旁路手术的效果研究。术后第7至9天，血浆胆固醇水平较初始检查时显著下降了42.8%。此后，血浆胆固醇水平有不同程度的上升，但在3个月时趋于稳定，平均值比术前低29.5%。在大多数患者中，使人虚弱的腹泻或严重体重减轻并非该手术的棘手问题。
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