Fogliani J, Domenget J F, Hohn B, Merignargues G, Bornstein N
Nouv Presse Med. 1982 Sep 18;11(36):2699-702.
In the case reported pulmonary Legionella infection was diagnosed by sputum cultures even though immunofluorescence tests were negative. The patient had positive Coomb's test due to circulating auto-antibodies which disappeared after he recovered. The course of the disease was prolonged by perforation of the coecum requiring excision of the colon and terminal ileostomy. Erythromycin had to be given intravenously. Pathological examination of the digestive tract lesions showed inflammatory colitis with presence of Legionella pneumophilia which seemed to have been responsible for the complication. This is the first time a digestive lesion caused by this organism is described, adding yet another extrapulmonary visceral involvement to those already reported and suggesting that Legionella may spread throughout the body.
在该报告病例中,尽管免疫荧光试验呈阴性,但通过痰培养诊断出肺部军团菌感染。患者因循环自身抗体导致库姆斯试验呈阳性,康复后这些抗体消失。由于盲肠穿孔需要切除结肠并进行末端回肠造口术,病程延长。必须静脉注射红霉素。消化道病变的病理检查显示为炎症性结肠炎,存在嗜肺军团菌,似乎是导致并发症的原因。这是首次描述由该病原体引起的消化道病变,为已报道的肺外内脏受累情况又增加了一种,并表明军团菌可能在全身扩散。