Denisova T S, Gibadulin R A
Vopr Virusol. 1982 Sep-Oct;27(5):77-83.
The paper describes physical maps of SA-7P DNA drawn with the help of XhoI, HpaI and BglII enzymes. DNA nucleotide sequence in the left side of the viral genome was found to have the length of 150 nucleotides. It contains codon for initiation of protein synthesis and coincides in this area with the known primary structure of Ela operon for human adenoviruses Ad5, Ad7, and Ad12. Study on the cells of two lines transformed by fragments of SA-7P DNA showed DNA of these cells to contain elements of the viral genome in different numbers of copies.
该论文描述了借助XhoI、HpaI和BglII酶绘制的SA - 7P DNA物理图谱。发现病毒基因组左侧的DNA核苷酸序列长度为150个核苷酸。它包含蛋白质合成起始密码子,并且在该区域与人类腺病毒Ad5、Ad7和Ad12的Ela操纵子的已知一级结构相符。对由SA - 7P DNA片段转化的两个细胞系的细胞研究表明,这些细胞的DNA含有不同拷贝数的病毒基因组元件。