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[人脑齿状核含铅性脂褐素沉着症]

[A Lead-containing lipomelanosis of the human nucleus dentatus cerebelli].

作者信息

Dietzmann K, Kemnitz P

出版信息

Zentralbl Allg Pathol. 1982;126(3-4):299-308.

PMID:7148185
Abstract

A case of a rare pigmentation of nucleus dentatus and stratum granulare cerebelli was investigated with microscopical and histochemical methods such as atom absorption and neutron activation analysis. The histochemical results of the analysis suggest that the pigment may belong to the group of melanin. The prepigments are rich in chromolipoids. The concentration of copper, zinc, iron and lead is increased. The larger content of lead has to be regarded as the very pathological symptom in the human cerebellum.

摘要

采用原子吸收和中子活化分析等显微镜和组织化学方法,对一例罕见的齿状核和小脑颗粒层色素沉着病例进行了研究。分析的组织化学结果表明,该色素可能属于黑色素组。前色素富含色脂类。铜、锌、铁和铅的浓度增加。铅含量较高必须被视为人类小脑的病理症状。

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