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[孕期吸烟导致的母婴体内一氧化碳情况]

[Carbon monoxide in mother and newborn infant from smoking during pregnancy].

作者信息

Neuberger M, Endler M, Resch W

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B. 1982 Aug;176(4):349-53.

PMID:7148208
Abstract

COHb-values of 24 newborn infants investigated (cord blood) were higher altogether than the corresponding maternal concentrations (venous) at birth. COHb in percent of saturable Hb ranged from 0.3 to 0.7 in 10 infants of nonsmokers and from 0.8-11.9 in 14 infants of smokers. Correlations between maternal and infant COHb were statistically significant. At birth the mean infant/maternal COHb ratio was 2.5. The significant correlations between maternal COHb during pregnancy (32.-38. week) and infant COHb at birth (cord blood) is an indication for the predictive value of such tests.

摘要

对24名新生儿(脐血)进行检测,其碳氧血红蛋白(COHb)值总体上高于出生时相应母亲的静脉血浓度。在10名非吸烟母亲的婴儿中,可饱和血红蛋白中COHb的百分比范围为0.3%至0.7%,在14名吸烟母亲的婴儿中为0.8%至11.9%。母亲和婴儿的COHb之间存在统计学上的显著相关性。出生时婴儿/母亲的COHb平均比值为2.5。孕期(第32至38周)母亲的COHb与出生时婴儿(脐血)的COHb之间的显著相关性表明了此类检测的预测价值。

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引用本文的文献

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Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air).慢性轻度一氧化碳暴露(空气中0.0025%)后大鼠发育中小脑氧化应激的证据。
BMC Neurosci. 2009 May 27;10:53. doi: 10.1186/1471-2202-10-53.