Breznock E M, Strack D
Am J Vet Res. 1982 Oct;43(10):1811-4.
Blood volume (BV) was determined in awake, nonsplenectomized (NSPX) and splenectomized (SPX) cats before and after hemorrhage (6 ml/kg). Each NSPX cat had a determined BV at least 10 ml/kg greater than the same cat after splenectomy. The mean BV of SPX cats was 43.4 +/- 8.94. ml kg (4.3% of body weight). The calculated RBC masses of NSPX and SPX cats were 17.0 +/- 4.07 and 12.2 +/- 1.12 ml/kg, respectively. Each NSPX cat had apparent RBC masses of 5 ml/kg greater than that of the same cat after splenectomy was done. At 1 hour after a hemorrhage, the BV and RBC masses determined in SPX cats were 46.7 +/- 12.1 and 9.7 +/- 1.90 ml/kg, respectively. Extravascular-to-intravascular fluid flux (calculated from RBC masses and plasma protein dilution) was approximately 0.80% of body weight. The indirect method with 51Cr-labeled RBC for BV determination was accurate and precise in awake, SPX cats; in awake, NSPX cats, the 51Cr-labeled RBC dilution method was precise, but not accurate. The spleen in the cat resulted in marked overestimations of BV and RBC masses.
在出血（6毫升/千克）前后，对清醒、未行脾切除术（NSPX）和已行脾切除术（SPX）的猫测定血容量（BV）。每只NSPX猫的测定血容量比脾切除术后的同一只猫至少高10毫升/千克。SPX猫的平均血容量为43.4±8.94毫升/千克（占体重的4.3%）。NSPX和SPX猫计算出的红细胞质量分别为17.0±4.07和12.2±1.12毫升/千克。每只NSPX猫的表观红细胞质量比脾切除术后的同一只猫高5毫升/千克。出血后1小时，SPX猫测定的血容量和红细胞质量分别为46.7±12.1和9.7±1.90毫升/千克。血管外至血管内的液体通量（根据红细胞质量和血浆蛋白稀释度计算）约为体重的0.80%。用51Cr标记红细胞的间接方法测定清醒SPX猫的血容量准确且精确；在清醒的NSPX猫中，51Cr标记红细胞稀释法精确但不准确。猫的脾脏导致血容量和红细胞质量明显高估。
