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Metastatic retinoblastoma and L-phenylalanine mustard-dianhydrogalactitol.

作者信息

Helson L, Kitchin F D, Abramson D, Ellsworth R M

出版信息

Anticancer Res. 1982 Jul-Aug;2(4):235-8.

PMID:7149653
Abstract

Retinoblastomas heterotransplanted to nude mice were shown to be sensitive to a combination of phenylalanine mustard and dianhydrogalactitol. A patient with metastatic retinoblastoma was treated with this combination and had a significant response with complete clinical clearance of her bone marrow and metastatic tumors. However, the patient's response was similar to that observed in nude mice; recurrences of tumors developed after complete clinical remission.

摘要

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