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通过淋巴细胞检测法检测人和小鼠孕期对胎儿抗原的细胞致敏作用。

Cellular sensitization in man and mice during pregnancy to fetal antigens as detected by lympholine assays.

作者信息

von Broen B, Albrecht S, Gryschek G, Morack G, Reinhöfer J, Schlott B, Pasternak G

出版信息

Arch Geschwulstforsch. 1981;51(4):371-4.

PMID:7316685
Abstract

Soluble extracts were prepared by the 3 M KC1 method from human mouse fetuses at different stages of development. As shown by macrophage electrophoretic mobility and by leukocyte migration inhibition tests a high percentage of pregnant women is sensitized to components of these extracts. The testing of pregnant mice of an inbred strain gave similar results. The available data support the view that some kind of cellular sensitization to fetal antigen may occur during pregnancy.

摘要

通过3M氯化钾法从不同发育阶段的人鼠胎儿制备可溶性提取物。巨噬细胞电泳迁移率和白细胞迁移抑制试验表明，高比例的孕妇对这些提取物的成分敏感。对近交系怀孕小鼠的测试也得到了类似结果。现有数据支持这样一种观点，即怀孕期间可能会发生某种对胎儿抗原的细胞致敏。

相似文献

1
Cellular sensitization in man and mice during pregnancy to fetal antigens as detected by lympholine assays.通过淋巴细胞检测法检测人和小鼠孕期对胎儿抗原的细胞致敏作用。
Arch Geschwulstforsch. 1981;51(4):371-4.
2
Reactivity in neoplasia, preneoplasia, and pregnancy of lymphocytes against fetal extracts: cross-reactions between man and mouse.肿瘤形成、肿瘤前期及妊娠状态下淋巴细胞对胎儿提取物的反应性：人与小鼠之间的交叉反应
J Natl Cancer Inst. 1982 Nov;69(5):997-1004.
3
Sensitization of leukocytes of cancer patients against fetal antigens: leukocyte migration studies.癌症患者白细胞对胎儿抗原的致敏作用：白细胞迁移研究。
J Natl Cancer Inst. 1979 Aug;63(2):285-93.
4
[Leukocyte migration inhibition and leukocyte adherence inhibition (LMI- and LAI-assay) in cancer patients by using preparations from human fetuses].[利用人胎儿制剂对癌症患者进行白细胞迁移抑制和白细胞黏附抑制（LMI和LAI检测）]
Acta Biol Med Ger. 1978;37(11-12):1747-57.
5
[Cross-reactivity of 3M KCl extracts of fetal tissue from various species in the macrophage electrophoresis mobility (MEM) test. I. Extracts from fetuses of mammals and one species of fowl].[巨噬细胞电泳迁移率（MEM）试验中不同物种胎儿组织3M氯化钾提取物的交叉反应性。I. 哺乳动物和一种禽类胎儿的提取物]
Arch Geschwulstforsch. 1983;53(2):93-8.
6
[Cross-reactivity of 3M KCl-extracts of fetal tissue from various species in the macrophage electrophoresis mobility test. II. Tissue extracts from lower vertebrates in various phases of development].[巨噬细胞电泳迁移率试验中不同物种胎儿组织的3M氯化钾提取物的交叉反应性。II. 不同发育阶段低等脊椎动物的组织提取物]
Arch Geschwulstforsch. 1983;53(5):401-6.
7
The leukocyte adherence inhibition test in tumor patients using 3M KCl extracts of fetal tissues as antigens.以胎儿组织的3M氯化钾提取物作为抗原，对肿瘤患者进行白细胞黏附抑制试验。
Arch Geschwulstforsch. 1982;52(5):341-8.
8
[Lymphocyte reactivity against fetal antigens during the growth and regression of experimental tumors].
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Lymphocyte reactivity in normal and malignant cell proliferation against a phylogenetically conserved antigen in fetal extracts.正常及恶性细胞增殖过程中淋巴细胞对胎儿提取物中一种系统发育保守抗原的反应性。
J Natl Cancer Inst. 1984 Apr;72(4):901-8.
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Heterogenicity and specificity of tumor associated antigens (TAA) and fetal antigens (FA) as detected by 51Cr-LAI test and EM test in mouse sarcomas.通过51Cr-LAI试验和EM试验检测小鼠肉瘤中肿瘤相关抗原（TAA）和胎儿抗原（FA）的异质性和特异性。
Arch Geschwulstforsch. 1981;51(6):481-4.