Itami Y, Akamatsu N, Tomita Y, Nagai M
Arch Orthop Trauma Surg (1978). 1982;100(3):183-9. doi: 10.1007/BF00442732.
It is essential that the prosthetic material should not be harmful to the human body, it should be strictly fitted to the body and it should have sufficient durability. To investigate those conditions of an artificial joints as mentioned above, it is important to have experimental studies using a model of the artificial joint in animals instead of a simulator. The authors have developed their own total hip prosthesis for a dog since 1970. These prostheses were fixed to the bone without bone cement. These dogs were killed periodically from 8 weeks to 3 years after surgery of total hip replacement. Not only were pathohistological studies on the joint capsule and bony tissue of the femur surrounding the prosthesis performed, but also scanning electron microscopic examination on capsule and the surface of the prosthetic head were performed. The results were excellent. Ther was no loosening or wear when the new type of acetabular socket with large spikes was used. On the other hand, in the case of the old type socket with its smooth surface and smaller spikes, loosening of the socket and prosthetic stem occurred within one year after surgery.
假体材料对人体无害、与身体紧密贴合且具有足够的耐用性至关重要。为研究上述人工关节的这些情况，使用动物人工关节模型而非模拟器进行实验研究很重要。自1970年以来，作者们为犬开发了自己的全髋关节假体。这些假体不用骨水泥固定在骨头上。在全髋关节置换手术后，这些犬在8周龄至3年期间定期处死。不仅对假体周围的关节囊和股骨骨组织进行了病理组织学研究，还对关节囊和假体头部表面进行了扫描电子显微镜检查。结果非常好。当使用带有大钉的新型髋臼杯时，没有松动或磨损。另一方面，对于表面光滑且钉较小的旧型髋臼杯，髋臼杯和假体柄在手术后一年内就出现了松动。
