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从动脉壁内皮表面去除唾液酸后，循环中的低密度脂蛋白和纤维蛋白原被动脉壁摄取增加。

Increased uptake of circulating low-density lipoproteins and fibrinogen by arterial walls after removal of sialic acids from their endothelial surface.

作者信息

Görög P, Born G V

出版信息

Br J Exp Pathol. 1982 Aug;63(4):447-51.

PMID:7150506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2040648/
Abstract

Carotid arteries of anaesthetized rabbits were perfused with neuraminidase to remove sialic acids from the endothelial surface. This resulted in significant accelerations of the uptake of low-density lipoproteins and of fibrinogen but not of albumin from the circulating blood.

摘要

用神经氨酸酶灌注麻醉兔的颈动脉，以去除内皮表面的唾液酸。这导致循环血液中低密度脂蛋白和纤维蛋白原的摄取显著加速，但白蛋白的摄取没有加速。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49b4/2040648/6f084758cb77/brjexppathol00106-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49b4/2040648/6f084758cb77/brjexppathol00106-0098-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49b4/2040648/6f084758cb77/brjexppathol00106-0098-a.jpg

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Increased uptake of circulating low-density lipoproteins and fibrinogen by arterial walls after removal of sialic acids from their endothelial surface.从动脉壁内皮表面去除唾液酸后，循环中的低密度脂蛋白和纤维蛋白原被动脉壁摄取增加。
Br J Exp Pathol. 1982 Aug;63(4):447-51.
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本文引用的文献

1
STUDIES OF THE COMPOSITION AND STRUCTURE OF SERUM LIPOPROTEINS: ISOLATION, PURIFICATION, AND CHARACTERIZATION OF VERY LOW DENSITY LIPOPROTEINS OF HUMAN SERUM.血清脂蛋白的组成与结构研究：人血清极低密度脂蛋白的分离、纯化及特性鉴定
Biochemistry. 1965 Mar;4:596-605. doi: 10.1021/bi00879a033.
2
Decreased anionic groups and increased permeability precedes deposition of immune complexes in the glomerular capillary wall.阴离子基团减少和通透性增加先于免疫复合物在肾小球毛细血管壁的沉积。
Am J Pathol. 1981 Nov;105(2):114-20.
3
Colloidal gold--low density lipoprotein conjugates as membrane receptor probes.
唾液酸在主动脉内皮腔面的分布不均。
Br J Exp Pathol. 1983 Aug;64(4):418-24.
4
Unusually high concentrations of sialic acids on the surface of vascular endothelia.血管内皮表面存在异常高浓度的唾液酸。
Br J Exp Pathol. 1985 Oct;66(5):543-9.
5
Differentiated microdomains of the luminal plasmalemma of murine muscle capillaries: segmental variations in young and old animals.小鼠肌肉毛细血管腔质膜的分化微区：幼年和老年动物的节段性变化
J Cell Biol. 1985 May;100(5):1396-407. doi: 10.1083/jcb.100.5.1396.
6
Reduced negative surface charge on arterial endothelium of diabetic rats.糖尿病大鼠动脉内皮细胞表面负电荷减少。
Diabetologia. 1988 Aug;31(8):618-20. doi: 10.1007/BF00264770.
7
Increases in plasma lysosomal enzymes in type 1 (insulin-dependent) diabetes mellitus: relationship to diabetic complications and glycaemic control.1型（胰岛素依赖型）糖尿病患者血浆溶酶体酶水平升高：与糖尿病并发症及血糖控制的关系
Diabetologia. 1992 Oct;35(10):991-5. doi: 10.1007/BF00401431.
胶体金-低密度脂蛋白复合物作为膜受体探针
Proc Natl Acad Sci U S A. 1981 Jan;78(1):368-71. doi: 10.1073/pnas.78.1.368.
4
Distribution of plasma proteins across the human aortic wall--barrier functions of endothelium and internal elastic lamina.血浆蛋白在人主动脉壁中的分布——内皮和内弹性膜的屏障功能
Atherosclerosis. 1980 Dec;37(4):579-90. doi: 10.1016/0021-9150(80)90065-9.
5
Effect of removing sialic acids from endothelium on the adherence of circulating platelets in arteries in vivo.去除内皮细胞唾液酸对体内动脉中循环血小板黏附的影响。
Proc R Soc Lond B Biol Sci. 1982 Mar 22;214(1197):471-80. doi: 10.1098/rspb.1982.0022.
6
Glomerular sialic acid and proteinuria in human renal disease.人类肾脏疾病中的肾小球唾液酸与蛋白尿
Lab Invest. 1973 Apr;28(4):477-81.
7
The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia.家族性II型高脂蛋白血症中低密度脂蛋白的代谢
J Clin Invest. 1972 Jun;51(6):1528-36. doi: 10.1172/JCI106949.
8
Permeability in atherosclerosis: fluorescence test in green light with trypan blue.动脉粥样硬化中的通透性：锥虫蓝绿光荧光试验
Atherosclerosis. 1977 Jul;27(3):353-9. doi: 10.1016/0021-9150(77)90045-4.
9
Receptor-mediated endocytosis: insights from the lipoprotein receptor system.受体介导的内吞作用：来自脂蛋白受体系统的见解
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3330-7. doi: 10.1073/pnas.76.7.3330.
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Eur J Biochem. 1979 Jan 2;93(1):51-5. doi: 10.1111/j.1432-1033.1979.tb12793.x.