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免疫球蛋白和补体蛋白向组织液和淋巴的毛细血管转运。

Capillary transport of immunoglobulins and complement proteins to the interstitial fluid and lymph.

作者信息

Olszewski W L, Engeset A

出版信息

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):57-65.

PMID:749810
Abstract

Low concentration of immunoglobulins G, A and M and complement component proteins were found in leg lymph of normal men. The lymph/serum ratios of different proteins ranged from 0.07 to 0.24 and depended on the molecular weight of the measured protein. Major variations in concentration were found dependent on the rate of capillary filtration and lymph formation. Hemolytic activity of total complement and of the 9 components were low, with the L/S ratio from 0.06 to 0.25. The C3H50 in lymph was much lower than of the remainder of components. Remarkably low immune adherence capacity of lymph C was noted.

摘要

在正常男性的腿部淋巴液中发现了低浓度的免疫球蛋白G、A和M以及补体成分蛋白。不同蛋白质的淋巴液/血清比值在0.07至0.24之间,且取决于所测蛋白质的分子量。发现浓度的主要变化取决于毛细血管滤过率和淋巴液生成率。总补体及9种补体成分的溶血活性较低,L/S比值在0.06至0.25之间。淋巴液中的C3H50远低于其余成分。值得注意的是,淋巴液C的免疫黏附能力很低。

相似文献

1
Capillary transport of immunoglobulins and complement proteins to the interstitial fluid and lymph.免疫球蛋白和补体蛋白向组织液和淋巴的毛细血管转运。
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):57-65.
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C1 inactivator and C3b inactivator in peripheral lymph of normal men.正常男性外周淋巴中的C1灭活剂和C3b灭活剂
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Haemolytic complement in peripheral lymph of normal men.正常男性外周淋巴中的溶血补体。
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引用本文的文献

1
Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex.淋巴源性趋化因子和其他低分子量分子通过特殊管道到达高内皮微静脉,而功能性屏障限制了进入淋巴结皮质中淋巴细胞微环境的通路。
J Exp Med. 2000 Nov 20;192(10):1425-40. doi: 10.1084/jem.192.10.1425.