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非同步睡眠期间心脏和血管交感神经活动的变化。

Changes in sympathetic activity to heart and blood vessels during desynchronized sleep.

作者信息

Futuro-Neto H A, Coote J H

出版信息

Brain Res. 1982 Dec 9;252(2):259-68. doi: 10.1016/0006-8993(82)90393-6.

DOI:10.1016/0006-8993(82)90393-6
PMID:7150953
Abstract

In mid-collicular decerebrate cats, the activity in sympathetic nerves to the heart, kidney, gastro-intestinal tract, pelvic viscera and blood vessels of skeletal muscle was examined during periods of extensor rigidity and during desynchronized sleep-like periods (DSp) either occurring spontaneously or induced by physostigmine sulphate. During DSp the activity in sympathetic vasoconstricstor fibres to muscle increased whereas that in the other sympathetic nerves decreased. The changes were present in vagotomized and sino-aortic denervated animals as well as in paralyzed preparations. It was concluded that the differential pattern of sympathetic activity was a characteristic of the tonic stage of desynchronized sleep and originated from a site in the central nervous system independently of afferent input.

摘要

在中脑水平去大脑的猫中,研究了在伸肌强直期间以及在自发出现或由硫酸毒扁豆碱诱导的去同步化睡眠样期(DSp)期间,心脏、肾脏、胃肠道、盆腔脏器和骨骼肌血管的交感神经活动。在DSp期间,支配肌肉的交感缩血管纤维活动增加,而其他交感神经的活动则减少。这些变化在迷走神经切断和窦主动脉去神经支配的动物以及瘫痪的标本中均存在。得出的结论是,交感神经活动的差异模式是去同步化睡眠紧张期的一个特征,并且起源于中枢神经系统的一个部位,与传入输入无关。

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