[Effect of L-DOPA on the emotional, behavioral and autonomic manifestations of acute nociceptive exposure].

Experiments on conscious cats have demonstrated that L-DOPA (25-50 mg/kg) does not change behavioral reactions evoked by dental pulp stimulation. L-DOPA (50 mg/kg) causes bradycardia accompanied by the increase in the cardiochronotropic baroreceptor reflex, inhibits the pressor and enhances heart rate nociceptive reactions. The effect of L-DOPA on the heart rate and baroreceptor reflexes is reversed by preliminary inhibition of peripheral DOPA-decarboxylase with benserazide (30 mg/kg).