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马生殖嗜血杆菌(传染性马子宫内膜炎病原体)主要抗原的特性分析

Characterization of the major antigens of Haemophilus equigenitalis (contagious equine metritis organism).

作者信息

Corbel M J, Brewer R A

出版信息

J Hyg (Lond). 1982 Dec;89(3):529-38. doi: 10.1017/s0022172400071102.

DOI:10.1017/s0022172400071102
PMID:7153516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2134243/
Abstract

Immunoelectrophoresis of ultrasonically disrupted Haemophilus equigenitalis (contagious equine metritis organism) cells against rabbit and equine antisera disclosed at least 11 precipitating antigens. Two of these, a polysaccharide and a lipopolysaccharide-protein complex, were of high molecular weight and located on the cell surface. The remaining antigens were intracellular and were small- to medium-sized proteins. The surface antigens were the most significant in relation to the serological response in infected horses. They also reacted with sera from apparently healthy cattle, but the reason for this was not determined. No serological cross-reaction between H. equigenitalis and species of Achromobacter and Moraxella was detected.

摘要

对超声破碎的马生殖道嗜血性杆菌(传染性马子宫内膜炎病原体)细胞与兔和马抗血清进行免疫电泳,结果显示至少有11种沉淀抗原。其中两种,一种多糖和一种脂多糖 - 蛋白质复合物,分子量较大,位于细胞表面。其余抗原位于细胞内,是中小分子蛋白质。表面抗原在感染马的血清学反应中最为重要。它们也与明显健康的牛的血清发生反应,但原因尚未确定。未检测到马生殖道嗜血性杆菌与无色杆菌属和莫拉菌属之间的血清学交叉反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/af50ca4d1e89/jhyg00027-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/e45ac7362a89/jhyg00027-0189-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/e6ca2b00c178/jhyg00027-0188-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/af50ca4d1e89/jhyg00027-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/e45ac7362a89/jhyg00027-0189-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/e6ca2b00c178/jhyg00027-0188-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06b2/2134243/af50ca4d1e89/jhyg00027-0190-a.jpg

相似文献

1
Characterization of the major antigens of Haemophilus equigenitalis (contagious equine metritis organism).马生殖嗜血杆菌(传染性马子宫内膜炎病原体)主要抗原的特性分析
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本文引用的文献

1
THE DETERMINATION OF PROTEIN MOLECULAR WEIGHTS OF UP TO 225,000 BY GEL-FILTRATION ON A SINGLE COLUMN OF SEPHADEX G-200 AT 25 DEGREES AND 40 DEGREES.在25摄氏度和40摄氏度下,通过在单一葡聚糖凝胶G - 200柱上进行凝胶过滤法测定高达225,000的蛋白质分子量。
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Ultrastructure of Haemophilus equigenitalis, causative agent of contagious equine metritis.马生殖器官传播性炎症病原体马生殖支原体的超微结构
Am J Vet Res. 1980 Jan;41(1):127-32.
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Serological identification of the bacterial agent of contagious equine metritis.
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A complement fixation test for antibody to the contagious equine metritis organism.马传染性子宫炎病原体抗体的补体结合试验。
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The application of bioluminescence and gas liquid chromatography for the rapid diagnosis of contagious equine metritis 1977.生物发光和气相色谱法在马传染性子宫炎快速诊断中的应用 1977年
Vet Rec. 1978 Sep 9;103(11):243-4. doi: 10.1136/vr.103.11.243.
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The experimental infection of ponies with contagious equine metritis.用马传染性子宫炎对小马进行实验性感染。
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