Kosugi T, Takagi I, Ariga Y, Okada S, Morimitsu T, Mihara H
Arch Otorhinolaryngol. 1982;236(3):211-5. doi: 10.1007/BF00454212.
Five parameters of blood coagulation and fibrinolysis, viz., levels of fibrinogen, fibrinolytic activity of euglobulin, fibrinogen and/or fibrin-degradation products (FDP), antiplasmin activity, and antithrombin activity, were measured in patients with cancer of the head and neck, and the results were compared with those of healthy adults. The fibrinogen content in cancer was significantly increased (p less than 0.001), the fibrinolytic activity of euglobulin significantly enhanced (p less than 0.001), the antiplasmin activity significantly reduced (p less than 0.05), the antithrombin activity significantly reduced (p less than 0.001), and the FDP level slightly increased, although the difference was not significant. The importance of the coagulation and fibrinolytic system in cancer of the head and neck is discussed.
对头颈部癌症患者测定了凝血和纤维蛋白溶解的五个参数，即纤维蛋白原水平、优球蛋白的纤维蛋白溶解活性、纤维蛋白原和/或纤维蛋白降解产物（FDP）、抗纤溶酶活性及抗凝血酶活性，并将结果与健康成年人的结果进行了比较。癌症患者的纤维蛋白原含量显著增加（p<0.001），优球蛋白的纤维蛋白溶解活性显著增强（p<0.001），抗纤溶酶活性显著降低（p<0.05），抗凝血酶活性显著降低（p<0.001），FDP水平略有升高，尽管差异不显著。本文讨论了凝血和纤维蛋白溶解系统在头颈部癌症中的重要性。
