二甲基氨基吡啶催化合成N-酰基谷胱甘肽衍生物
Synthesis of N-acylglutathione derivatives by dimethylaminopyridine catalysis.
作者信息
D'Silva C, Al-Timari A, Douglas K T
出版信息
Biochem J. 1982 Nov 1;207(2):329-32. doi: 10.1042/bj2070329.
Abstract
A general procedure, involving 4-dimethylaminopyridine-catalysed acylation of the amino groups in the appropriate S-blocked glutathione, is reported for the preparation of N-blocked derivatives of glutathiones.
摘要
报道了一种通用方法，该方法涉及在合适的S-保护谷胱甘肽中，通过4-二甲氨基吡啶催化氨基的酰化反应来制备谷胱甘肽的N-保护衍生物。
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本文引用的文献
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The oxidation of glutathione with formic acid and hydrogen peroxide.
Experientia. 1963 Jun 15;19:324-7. doi: 10.1007/BF02150437.
2
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Biochem Biophys Res Commun. 1980 Jul 16;95(1):446-52. doi: 10.1016/0006-291x(80)90758-5.
3
Role of the N-terminus of glutathione in the action of yeast glyoxalase I.谷胱甘肽N端在酵母乙二醛酶I作用中的角色
Biochem J. 1982 Nov 1;207(2):323-29. doi: 10.1042/bj2070323.
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Glutathione derivatives as inhibitors of glutaredoxin and ribonucleotide reductase from Escherichia coli.谷胱甘肽衍生物作为大肠杆菌谷氧还蛋白和核糖核苷酸还原酶的抑制剂
FEBS Lett. 1982 Feb 8;138(1):59-61. doi: 10.1016/0014-5793(82)80394-3.
5
A photoaffinity label derivative of glutathione and its inhibition of glyoxalase I.谷胱甘肽的一种光亲和标记衍生物及其对乙二醛酶I的抑制作用。
FEBS Lett. 1980 Feb 11;110(2):262-4. doi: 10.1016/0014-5793(80)80087-1.
6
Studies on the inhibition of glyoxalase I by S-substituted glutathiones.S-取代谷胱甘肽对乙二醛酶I的抑制作用研究。
J Med Chem. 1971 May;14(5):402-4. doi: 10.1021/jm00287a006.
7
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