Gregor Z, Ryan S J
Graefes Arch Clin Exp Ophthalmol. 1982;219(5):205-8. doi: 10.1007/BF00231236.
The competence of blood retinal barrier at the level of retinal pigment epithelium (RPE) and retinal capillaries was studied 30 min, 24 h, 3 days, and 7 days after experimental blunt eye injury in the pig, using horseradish peroxidase (HRP). Leakage of HRP into the outer retinal layers was observed in association with disrupted RPE in the first three days after injury. No HRP leakage was seen 7 days after the trauma and the retinal vessels remained competent throughout the study. It is suggested that extracellular edema occurs in the early stages of commotio retinae due to the disruption of blood retinal barrier at the level of the RPE.
在猪眼钝挫伤实验后的30分钟、24小时、3天和7天，使用辣根过氧化物酶（HRP）研究视网膜色素上皮（RPE）和视网膜毛细血管水平的血视网膜屏障功能。损伤后的前三天，观察到HRP渗漏到视网膜外层，伴有RPE破坏。创伤后7天未见HRP渗漏，且在整个研究过程中视网膜血管功能保持正常。提示视网膜震荡早期由于RPE水平的血视网膜屏障破坏而发生细胞外水肿。
