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用左旋咪唑和甲苯达唑对大鼠马来血管圆线虫感染进行化疗和化学预防

Chemotherapy and chemoprophylaxis of Angiostrongylus malaysiensis infection in rats with levamisole and mebendazole.

作者信息

Ambu S, Kwa B H, Mak J W, Singh K I

出版信息

Folia Parasitol (Praha). 1982;29(4):361-4.

PMID:7160790
Abstract

The chemoprophylactic and chemotherapeutic effects of levamisole and mebendazole on Angiostrongylus malaysiensis infection in rats were studied. Both drugs were ineffective in preventing infection while the post-infection treatment showed 100% efficacy. Furthermore, levamisole and mebendazole when given in combination appeared to have an antagonistic effect.

摘要

研究了左旋咪唑和甲苯咪唑对大鼠马来丝虫感染的化学预防和化学治疗作用。两种药物在预防感染方面均无效,而感染后治疗显示出100%的疗效。此外,左旋咪唑和甲苯咪唑联合使用时似乎具有拮抗作用。

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