Izumi A K
Arch Dermatol Res. 1982;272(3-4):387-91. doi: 10.1007/BF00509070.
The sixth case of an allergic contact gingivostomatitis to gold crowns previously misdiagnosed as erosive lichen planus is reported. Patch tests to gold chloride (0.5%) and 0.05 cm3 intradermal gold sodium thiomalate (Myochrysine 50 mg/cm3) were positive at 48-72 h. Histopathology of the allergic contact gingivitis revealed a pseudolymphomatous inflammatory dermal reaction with a dense lymphohistiocytic and plasma cell infiltrate. Removal of the gold crowns resulted in a gradual resolution of the gingivostomatitis in 4-6 months, and the patient has remained free of clinical disease for over 3 years. A review of the reported cases of allergic gingivostomatitis to gold crowns revealed that each patient clinically presented with an erosive and ulcerative inflammatory response was usually associated with a clinical history of gold jewelry intolerance.
本文报告了第六例对金冠发生过敏接触性龈口炎的病例，该病例此前被误诊为糜烂性扁平苔藓。对氯化金（0.5%）和0.05 cm³皮内注射硫代苹果酸金钠（硫代苹果酸金钠50 mg/cm³）进行斑贴试验，在48 - 72小时呈阳性。过敏性接触性牙龈炎的组织病理学显示为假淋巴瘤样炎症性皮肤反应，伴有密集的淋巴细胞、组织细胞和浆细胞浸润。去除金冠后，龈口炎在4 - 6个月内逐渐消退，该患者已3年多无临床疾病。对已报道的金冠过敏接触性龈口炎病例的回顾显示，每名临床呈现糜烂性和溃疡性炎症反应的患者通常都有对金首饰不耐受的临床病史。
