Muto N, Tani S
Biochem Genet. 1982 Dec;20(11-12):1189-93. doi: 10.1007/BF00498942.
A pepsinogen (Pg 1) polymorphism was observed in gastric mucosal samples of Wistar rats by polyacrylamide slab gel electrophoresis. Three phenotypes were observed: S (a slow-moving band), F (a fast-moving band), and FS (both bands). Pg 1 variation was controlled by a pair of codominant alleles at a single autosomal locus. Interstrain variation of Pg 1 was studied in five strains of laboratory rats. Genetic variation of Pg 1 was detected only in the Wistar strain.
通过聚丙烯酰胺平板凝胶电泳在Wistar大鼠的胃黏膜样本中观察到胃蛋白酶原(Pg 1)多态性。观察到三种表型:S(一条慢迁移带)、F(一条快迁移带)和FS(两条带)。Pg 1变异由常染色体单一位点上的一对共显性等位基因控制。在五种实验大鼠品系中研究了Pg 1的品系间变异。仅在Wistar品系中检测到Pg 1的遗传变异。