Correa P, Haenszel W, Tannenbaum S
Natl Cancer Inst Monogr. 1982;62:129-34.
The epidemiology of stomach cancer is reviewed and key events identified, including migrant population studies, the Jarvi-Laurén classification of gastric carcinoma, and application of this classification to comparative autopsy studies. The gradual transformation to the epidemiology of precancer lesions is sketched, and the studies in Colombia contributing to this transformation are described. An etiologic model based on the formation of carcinogenic N-nitroso compounds is proposed. Future work for investigators in the Department of Nariño (Colombia) to test and evaluate this hypothesis is described.
本文回顾了胃癌的流行病学并确定了关键事件，包括流动人口研究、胃癌的贾维-劳伦分类以及该分类在比较尸检研究中的应用。概述了向癌前病变流行病学的逐步转变，并描述了哥伦比亚有助于这一转变的研究。提出了一种基于致癌性N-亚硝基化合物形成的病因模型。描述了纳里尼奥省（哥伦比亚）研究人员为检验和评估这一假设而开展的未来工作。
