Lachapelle J M, Tennstedt D, Burtonboy G
Ann Dermatol Venereol. 1982;109(11):939-46.
Blue or black tattoos were observed in five patients who had received several intradermal injections (of a lidocaine solution or of a triamcinolone acetonide suspension) with the Dermo-Jet. A histological examination revealed the presence of black masses, rounded or elongated, different in size, distributed throughout dermal tissue. Additionally, conglomerates of black grains in the cytoplasm of histiocytes and of pericytes are precisely observed in semi-thin sections. It has been proved by several investigations that these foreign particles are not of metallic nature. It can be concluded from electron microscopic studies that the particles are fragments of black rubber, from the upper joint of the reservoir. Indeed, some rubber fragments are leached into the reservoir. Some of these are passing through the wire-mesh filter of the nozzle (with the solution or the suspension) when injections are made. Therefore, they are injected intradermally and are permanently tattooing the skin.
在5名接受过多次使用Dermo-Jet进行皮内注射(利多卡因溶液或曲安奈德混悬液)的患者身上观察到了蓝色或黑色纹身。组织学检查显示存在黑色团块,呈圆形或椭圆形,大小各异,分布于整个真皮组织。此外,在半薄切片中可精确观察到组织细胞和周细胞的细胞质中有黑色颗粒聚集体。多项研究已证明这些外来颗粒并非金属性质。从电子显微镜研究可以得出结论,这些颗粒是来自储液器上部接头的黑色橡胶碎片。事实上,一些橡胶碎片会渗入储液器。在注射时,其中一些会随溶液或混悬液通过喷嘴的金属丝网过滤器。因此,它们被皮内注射并永久性地在皮肤上留下纹身。