O'goshi Ken-ichiro, Suihko Christian, Serup Jørgen
Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.
Skin Res Technol. 2006 May;12(2):94-8. doi: 10.1111/j.0909-752X.2006.00199.x.
BACKGROUND/AIMS: In vivo confocal laser scanning microscopy (CLSM) is a new method for high-resolution imaging of intact skin in situ. Horizontal mapping of the outer skin is provided (magnification x 1000).
Tattooing is popular all over the world; however, tattooed skin has not been studied in using CLSM.
Tattoos in two volunteers were studied using the Vivascope1500 of Lucid Inc. Subepidermal massive deposits of dense, clustered pigment granules up to about 3 mum in size corresponding to black tattoos, and more scarce and diffuse deposits, corresponding to red, blue and green tattoos, were observed. Diffuse pigment granules tended to accumulate in the outer dermis underneath the level of the basement membrane zone.
Dermal pigments from tattoos can be imaged in vivo using CLSM. This application of CLSM has an important future potential for pre-evaluation of tattoos before laser removal, predicting good or poor outcome of laser removal.
背景/目的：体内共聚焦激光扫描显微镜（CLSM）是一种对完整皮肤进行原位高分辨率成像的新方法。它可提供皮肤外层的水平图谱（放大倍数为1000倍）。
纹身风靡全球；然而，尚未有人使用CLSM对纹身皮肤进行研究。
使用Lucid公司的Vivascope1500对两名志愿者的纹身进行了研究。观察到皮下有大量密集的、聚集的色素颗粒沉积，大小约达3微米，对应黑色纹身，而红色、蓝色和绿色纹身的色素沉积则较为稀少且分散。弥漫性色素颗粒倾向于在基底膜带水平以下的真皮外层积聚。
纹身的真皮色素可通过CLSM进行体内成像。CLSM的这一应用在激光去除纹身前的预评估以及预测激光去除效果的好坏方面具有重要的未来潜力。
